Validating the Potential of abenacianine sodium injection (VGT-309) in Solid Tumors
In Phase 1 and 2 clinical studies, abenacianine sodium injection was shown to be safe and well- tolerated at all doses studied. Other important clinical highlights included:
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abenacianine sodium injection imaging identified visually non-discernable, non-palpable tumors in real time.
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abenacianine sodium injection visualization showed an unexpected positive lymph node that the surgeon removed and subsequently confirmed as containing malignancy.
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abenacianine sodium injection tumor visualization allowed for preservation of healthy tissue following prior lung cancer surgery.
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abenacianine sodium injection imaging identified a colorectal cancer tumor that had metastasized to a patient’s lung, was not visible on PET and CT imaging, and the surgeon would have otherwise missed.
Phase 1 and and 2 Clinical Studies Have Yielded Compelling Data
Results suggest abenacianine sodium injection is safe and well-tolerated, and labels human lung tumors during resection surgeries.
Phase 2 multi-center safety and efficacy study for cancer in the lung (NCT06145048)
Phase 2 clinical study in lung cancer surgery ongoing (NCT05400226)
Phase 2 dose-ranging study in lung cancer surgery ongoing (ACTRN12621000301864)
Phase 1 clinical study for safety in healthy human volunteers completed (ACTRN12620000948998)
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1. Scientific manuscript in preparation
